Myasthenia Gravis (MG)

(See separate entry for Mild generalized – adult and ocular)

RecommendationsIVIG is recommended as first-line treatment in moderate-severe MG or in myasthenic crisis.

IVIG in combinations with immunosuppressive therapy can be considered in refractory cases.
Dose/Frequency of AdministrationInduction (before surgery or during myasthenic crisis): 1 to 2 g/kg adjusted body weight divided over 1 to 5 days (maximum 1 g/kg/day). 

Maintenance: 0.4 to 1 g/kg adjusted body weight every 4 to 6 weeks.