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Hospital Distribution of Blood Components and Products

Provincial Redistribution Program for Transfusion Services in Ontario

The Provincial Redistribution Program was established to provide a mechanism for hospitals to safely redistribute blood components and plasma protein and related products(PPRP) with an aim of reducing the overall number of components and PPRP that outdate at Ontario Hospitals.

Inventory phase timeline infographic

The Ontario Regional Blood Coordinating Network (ORBCoN) and the Factor Concentration Redistribution Program (FCRP) collaborated with stakeholders in Ontario and other provincial blood offices to validate shipping containers used by hospitals. These containers are crucial for redistributing and transferring blood components and PPRP between facilities. By implementing these strategies, ORBCoN and FCRP have maximized utilization, minimized wastage, and helped ensure safe and equitable access to all products for all patients.

In 2008, hospitals in Ontario were provided with Credo ProMed/GoldenHourTM shipping containers, validated for redistribution purposes. Hospitals were also using the J82 and E38 shipping containers for distribution of blood components and PPRP. In 2017, Canadian Blood Services (CBS) introduced their new insulated shipping container (ISC) for dedicated CBS usage but continued to provide the J82 and E38 containers to hospitals for redistribution and transfers.

A provincial working group developed and evaluated the processes for redistributing blood components and PPRP. Standardized procedures included in this toolkit ensure the security and safety of the redistributed blood components and PPRP during shipment.

In 2017, ORBCoN collaborated with hospital sites to validate the J82 and E38 shipping containers. The purpose of the validation was to confirm that acceptable temperatures and traceability were maintained when redistributing or transferring blood components or PPRP between facilities with a new established packing configuration based on hospital pre-conditioning.

The redistribution toolkit:

  • Guides hospitals in participating in the provincial redistribution program.
  • Provides standardized process and procedure templates.
  • Supports regulated practices for distribution including the transfer of blood components and PPRP with patients.
  • Allows hospitals to tailor their practice to meet the hospital’s specific needs and comply to regulatory demands.
  • Posts validation and verification reports pertaining to the redistribution program.


Using historical utilization and evidence‑based tools to set appropriate target inventory levels.

Why determining inventory matters

Effective inventory management is essential for balancing patient care, safety, and maintaining an adequate blood supply across Ontario hospitals.

This section provides tools to help facilities assess usage patterns and determine optimal inventory levels.

Key Principles of Inventory Management

BALANCESTEWARDSHIPCONTINUOUS MONITORINGVALUE RESOURCE
Maintain inventory sufficient for daily/emergency needs while avoiding unnecessary stockpiling.1Avoid overstocking or stockpiling to reduce unnecessary discards due to outdating or waste.Monitor inventory at regular intervals. Adjust inventory when hospital services or surgical volumes change.2Treat blood components as a valuable and limited resources.

Quality Indicators for Monitoring Inventory Levels

  1. Rate of Outdating Components:
    KPI Key Performance Indicator ...High outdating suggests overstocking, while low rates may indicate inadequate inventory if redistribution is not performed at your hospital.  Review the provincial utilization graphs to compare outdate rates. Goal is to be meeting or below the provincial average.
  2. Number of Urgent Requests
    Frequent “STAT” requests to blood supplier may indicate insufficient inventory level.
  3. Frequency of Redistribution of Components.
    Excessive redistribution to maintain low outdate rate may indicate unnecessarily high inventory levels. Review the provincial utilization graphs graphs to compare outdate rates. Goal is to be meeting or below the provincial average.

Tools to Determine Appropriate Inventory Levels

Inventory management color icon Royalty Free Vector ImageUtilizing the Canadian Blood Services (CBS) portal3 to report monthly disposition of blood components and products helps hospitals recognize success and improvement in their blood utilization practices. One of the tools provided is the automatic calculation of average daily demand for components and a suggested days on hand estimation tool. In Ontario, it is highly encouraged for all hospitals to report their monthly disposition. For those sites that may not access this portal below are some ways to determine your inventory targets.

Red Blood Cells (RBC)
Weekly Usage Track weekly RBC usage by ABO and Rh type over six months. Exclude the highest week and calculate the average for ideal stock[TC1] [LA2] . Ideal weekly inventory = # of units used/ (# of weeks tracked – 1)
Average Daily Red Cell Demand (ADRD) Record daily usage by ABO and Rh type over one quarterCalculate the average daily red cell demand (ADRD) Average daily redcell demand = # of units used/90 days (4) Use 6 to 9 days on hand (DOH) [LA3] x ADRD as your optimal inventory, adjusting for distance to the blood supplier (e.g., 10-12 DOH x ADRD for more remote sites)If you are closer to blood supplier (<1hour) a 6 DOH x ADRD would be reasonable
Inventory Calculator Tools like ORBCoN’s RBC calculator provide quick estimates based on annual transfusion numbers. Customize ABO proportions to reflect local patient population or use the Canadian distribution of blood groups5 to create your estimated inventory. The calculator will calculate 1-day up to 10-day inventory. Tips: Minimum inventory should support basic emergency patient care, typically at least 4 group O Rh-positive and 2 group O Rh-negative. Adjustments may depend on patient demographics, proximity to other hospitals, the frequency of transfusions, and delivery times from the blood supplier.If a 10-day inventory calculation yields fewer than 2 units, it is generally unnecessary to routinely stock that blood group and Rh type. It is best practice to order group and Rh specific RBCs on demand for patient use, when possible, rather than using non-group specific units.
Platelets (PLT) [LA4] 
Average Daily Platelet Demand Not all hospitals need to stock platelets. Order as needed from the blood supplier. Hospitals with frequent or large trauma programs may choose to maintain on-site inventory to reduce delays and limit the need for frequent deliveries.
Inventory Calculator Tools like ORBCoN’s PLT calculator provide quick estimates based on average daily usage. While PLT demand can vary daily, the tool uses annual usage data to provide a starting point or validate current inventory levels. Tips: In general, a 1 to 2 DOH is optimal.Standing orders may be offered by the blood supplier to help hospitals maintain inventory levels to maximize ordering and delivery efficiencies.

Managing Inventory During Blood Shortages[KS5] 

Shortage - Free signaling iconsDuring shortages, hospitals should adjust inventory to maximize total blood inventory available provincially, for life-threatening cases. The Ontario Hospital Toolkit for Emergency Blood Management6 provides detailed guidance to determine appropriate target levels of inventory during the different phases of a blood shortage.

Green Phase = Optimal Inventory
Green Advisory Phase (reduce by 10%) = Monitor inventory closely
Amber Phase (reduce by 25%) = Reduce inventory to conserve supply
Red Phase (reduce by 75%) = Emergency level inventory only
  • Inventory Calculator for Red Cells

    A tool for hospitals to use to perform a very quick estimate of what their ideal RBC inventory levels should be. By entering your annual number of RBC units transfused (for the most current year), an estimate of average daily use will be calculated by the formula locked in to the table.

    By entering the disposition information reported into the CBS disposition portal for your hospital into this calculator, you can determine your green, amber and red phase inventory levels. If your hospital is able to report disposition to CBS by ABO/Rh, then ABO proportion calculation will be based on what is actually transfused at your site. If your site does not report by ABO/Rh then your ABO proportion will be calculated based on current Canadian population probabilities for ABO/Rh.

  • Inventory Calculator for Platelets

    This tool will serve as a broad estimate of the suggested levels if stock is held on site.

  • Calculating Blood Inventory Levels

    Calculating your Blood Component Inventory. How do you decide your ideal stock levels?

References:

  1. Chapman JF. Unlocking the essentials of effective blood inventory management. Transfusion 2007;47:190S-196S.
  2. Blood and Inventory Management Resources | National Blood Authority [Internet]. Blood.gov.au. 2024 [cited 2025 Jan 15]. Available from: https://www.blood.gov.au/blood-products/blood-product-management/blood-and-inventory-management-resources
  3. Canadian Blood Services Hospital Portal
  4. The National Plan for Management of Shortages of Labile Blood Components [Internet]. [cited 2025 Jan 21]. Available from: https://nacblood.ca/sites/default/files/2023-09/2023-09-26%20National%20Plan%20for%20Management%20of%20Shortages%20of%20Labile%20Blood%20Components.pdf
  5. How rare are blood types? [Internet]. www.blood.ca. Available from: https://www.blood.ca/en/stories/blood-types-canada-how-common-or-rare-are-they
  6. Ontario Contingency Plan for the Management of Blood Shortages Version 3 [Internet]. 2016 [cited 2025 Jan 21]. Available from: https://transfusionontario.org/wp-content/uploads/2020/06/2.1-Ontario-Plan-3_Plan_2016-12-21FINAL-REVISED.pdf

Step 2: Review Shipment Requirements and Distribution/Redistribution Processes

Ensure safe and reliable shipment of blood components and PPRP by following standardized courier practices and validated shipping procedures. This step guides hospitals in selecting appropriate courier systems, using provincially validated containers, and maintaining temperature control during transport—especially in extreme weather. It also highlights the need for site‑specific operational verification and regular temperature checks to meet accreditation and safety requirements. Together, these processes help support consistent, compliant, and efficient distribution/redistribution across all participating hospitals.

Hospital Couriers

  • Use established corporate/intra-organization courier systems to support distribution of blood components and products. Existing routes that carry documents or samples can also transport shipping containers between sites.
  • If no courier system exists for a group of hospitals, investigate potential distribution processes.
  • When redistribution is facilitated by ORBCoN/FCRP, courier costs are covered by ORBCoN or FCRP.

Shipping Container Validation Results

J82, E38 and Credo ProMed™ containers have been validated provincially for blood components and PPRP. Pre-conditioning of icepacks/gel packs per the validation protocol maintains acceptable temperatures for specified durations. Credo ProMed™ is the current name of the Golden Hour MTS 24-2 container.

Table 1- Shortest Time J82 Shipping Container Maintained Acceptable Temperature in various ambient temperature conditions

PayloadAcceptable Shipping Temp<-30°C1 – 6°C19- 25°C> +30°C
1-8 RBCs1°C -10°C)3 hours24 hours12 hours8 hours
1 – 8 PPRPs2°C -25°C2 hours24 hours24 hours24 hour

Table 2 – Shortest Time E38 Shipping Container Maintained Acceptable Temperature in various ambient temperature conditions

PayloadAcceptable Shipping Temp<-30°C 1- 6°C19 -25°C> +30°C
1 – 6 Plts20°C -24°C2 hours5 hours24 hours9 hours
1 – 8 PPPs19°C -25°C24 hours24 hours24 hours6 hours

Table 3: Overall average temperature in laboratory validation test for Golden Hour MTS 24-2 ([KS1] [KS2] Credo ProMedÔ)

Payload Average Temperature for payload at -20°C  Average Temperature for payload at 4°CAverage Temperature for payload at 22°CAverage Temperature for payload at 40°C
1 RBC unit 5.5 C5.4 C5.0 C5.4 C
4 RBC units 5.6 C6.5 C4.7 C5.1 C

Due to the limited time the containers maintain acceptable temperatures in extreme ambient temperatures, it is recommended that the blood components and PPRP be transported within the confines of the vehicle’s interior, where ambient temperatures are more controlled. Facilities should confirm with their courier providers that the shipping container can be placed inside the vehicle’s passenger area.

*Note: When extreme temperatures are forecasted, it is recommended that redistribution is delayed until  acceptable ambient temperature is anticipated.

 [KS2]Or should we set up table 3 in the same format as table 1&2

Temperature verification data for the shipping containers used in the Provincial Redistribution Program for Transfusion Services in Ontario.

Revised March 2026

This table lists all hospitals that have completed and submitted the Memorandum of Understanding for redistribution of blood components and plasma protein and related products within Ontario.

Site NameDate Signed
(dd/mm/yyyy)
Alexandra Hospital13/06/2023
Alexandra Marine and General Hospital07/07/2023
Almonte General Hospital25/07/2024
Anson General Hospital05/02/2025
Arnprior Regional Health26/10/2023
Atikokan General Hospital17/09/2024
Bingham Memorial Hospital 05/02/2025
Blanche River Health22/07/2024
Bluewater Health22/09/2023
Brant Community Healthcare20/06/2023
Brightshores Health System07/06/2024
Brockville General Hospital23/06/2023
Cambridge Memorial Hospital22/07/2024
Campbellford Memorial Hospital13/06/2023
Carleton Place District Memorial Hospital25/07/2024
Chatham-Kent Health Alliance – Chatham site18/07/2023
Chatham-Kent Health Alliance – Wallaceburg Site18/07/2023
Children’s Hospital of Eastern Ontario15/12/2023
Collingwood General and Marine Hospital17/07/2023
Cornwall Community Hospital 20/02/2025
Deep River and District Hospital 05/02/2025
Dryden Regional Health Centre02/12/2025
Erie Shores Healthcare 24/07/2024
Espanola Regional Hospital and Health Centre28/08/2024
Georgian Bay General Hospital12/06/2023
Geraldton District Hospital25/07/2024
Glengarry Memorial Hospital19/07/2024
Grand River Hospital12/10/2023
Groves Memorial Hospital12/08/2024
Guelph General Hospital16/06/2023
Haldimand War Memorial Hospital14/08/2024
Halton Healthcare – Oakville Trafalgar Memorial Hospital13/02/2025
Halton Healthcare – Georgetown Hospital 19/02/2025
Halton Healthcare – Milton District Hospital19/02/2025
Hamilton Health Sciences23/07/2024
Hanover and District Hospital11/10/2023
Hawkesburry General Hospital10/11/2023
Headwaters Health Care Centre18/07/2024
Health Sciences North25/08/2023
Hôpital Montfort19/06/2023
Hornepayne Hospital18/06/2024
Humber River Health06/02/2025
Huron Perth Health Alliance – Clinton Public Hospital07/07/2023
Huron Perth Health Alliance  – Seaforth07/07/2023
Huron Perth Health Alliance – St. Mary’s07/07/2023
Huron Perth Health Alliance – Stratford General Hospital07/07/2023
Joseph Brant Hospital 06/02/2025
Kemptville District Hospital25/07/2024
Kingston Health Science Centre24/07/2024
Lady Dunn Hospital14/06/2023
Lady Minto Hospital13/06/2023
Lake of the Woods District Hospital21/10/2024
Lakeridge Health Corporation18/07/2024
Lennox and Addington County General Hospital19/06/2023
Listowel Memorial Hospital10/07/2023
London Health Sciences Centre – University Hospital23/10/2024
London Health Sciences Centre – Victoria Hospital23/10/2024
Mackenzie Health30/07/2024
Manitoulin Health Centre16/10/2024
Hôpital De Mattawa Hospital 06/02/2025
Michael Garron Hospital02/10/2023
Mount Sinai07/10/2024
Muskoka Algonquin Healthcare – SMMH & HMDH12/06/2023
Niagara Health Systems12/06/2023
Nipigon District Memorial Hospital11/02/2025
North Bay Regional Health Centre19/06/2024
North of Superior Healthcare Group (NOSH) – McCausland Hospital Site22/07/2024
North Shore Health Network17/08/2023
North York General Hospital30/09/2025
Northumberland Hills Hospital12/07/2023
Notre-Dame Hospital06/12/2023
Oak Valley Health – Markham Stouffville Hospital16/10/2024
Orillia Soldiers Memorial Hospital 14/06/2023
Pembroke Regional Hospital 06/02/2025
Peterborough Regional Health Centre15/06/2023
Perth and Smiths Falls District Hospital 19/09/2024
Queensway Carleton Hospital12/06/2023
Quinte Healthcare (Trenton, Prince Edward County, Belleville, North Hastings) 06/02/2025
Red Lake Margaret Cochenour Memorial Hospital19/07/2024
Renfrew Victoria Hospital26/10/2023
Riverside Health Care Facilities – Fort Frances 12/03/2025
Ross Memorial Hospital16/06/2023
Santé Manitouwadge Health16/02/2024
Sault Area Hospital14/06/2023
Scarborough Health Network09/01/2024
Sensenbrenner Hospital 05/02/2025
Sioux Lookout Meno Ya Win Health Centre23/10/2024
South Bruce Grey Health Centre – Chesley, Durham, Kincardine, Walkerton07/07/2023
South Huron Hospital07/07/2023
Southlake Regional Health Centre08/09/2023
Stevenson Memorial Hospital15/09/2023
Strathroy Middlesex General Hospital25/06/2024
St Francis Memorial Hospital26/10/2023
St Joseph’s General Hospital28/08/2024
St Joseph’s Health Centre24/07/2024
St Joseph’s Healthcare Hamilton 23/07/2024
St Mary’s General Hospital22/07/2024
St Michael’s Hospital15/06/2023
St Thomas Elgin General Hospital19/07/2024
Sunnybrook Hospital21/08/2023
Temiskaming Hospital12/06/2023
The Hospital for Sick Children20/06/2023
The Ottawa Hospital15/02/2024
Thunder Bay Regional Heatlh Sciences Centre20/09/2023
Tillsonburg District Memorial Hospital13/06/2023
Timmins and District Hospital14/06/2023
Trillium Health – Credit Valley Hospital13/06/2023
Trillium Health – Mississauga Hospital01/08/2025
University Health Network – Princess Margaret Hospital24/10/2024
University Health Network – Toronto General Hospital24/10/2024
University Health Network – Toronto Western Hospital24/10/2024
Uxbridge Hospital – Oak Valley Health21/02/2024
Weeneebayko Area Health Authority (WAHA) 17/03/2025
Wellington Healthcare- Groves Memorial Site 10/11/2023
Wellington Healthcare- Louise Marshall & Palmerston Sites 11/03/2025
West Haldimand General Hospital14/08/2024
West Nipissing General Hospital27/08/2024
West Parry Sound Health Centre21/08/2024
William Osler Health Systems – Brampton Civic Hospital20/06/2023
William Osler Health Systems – Etobicoke General Hospital20/06/2023
Wilson Memorial General Hospital22/07/2024
Winchester District Memorial Hospital26/07/2023
Windsor Regional Hospital – Metropolitan and University Sites26/06/2023
Wingham and District Hospital10/07/2023
Woodstock Hospital12/06/2023

Revised October 2024

The purpose of this Agreement is to establish cooperation implementing a redistribution program for blood components and Plasma Protein and Related Products (PPRP) nearing expiry, between hospitals that receive blood components and PPRP from Canadian Blood Services (CBS), to reduce wastage of these valuable and limited resources.  

Whereas this agreement is between one participating hospital or corporation, and ORBCoN and FCRP, inherent into this agreement is cooperation between participating hospitals as explained under Goals and Forms of Cooperation. 

Revised 2023

Revised 2023

Revised 2023

Revised 2023

Revised 2023

Revised 2023

A general protocol for cleaning/disinfecting shipping containers and shipping materials used for redistribution of blood components and products (May 2020)

Revised 2018

Revised 2018

Revised 2018

Updated October 2023

Revised 2023

Training on how to report your near to expiring Plasma Protein and Related Products that need to be reditributed