Neonatal hemochromatosis, prevention

Recommended Indications in which IG can be used

Recommendations	IVIG is recommended for: Neonates with hemochromatosis confirmed by findings of high iron on biopsy or by MRI demonstration of iron overload; and Pregnant women who have had a previous pregnancy affected by neonatal hemochromatosis.
Dose/Frequency of Administration	Neonatal: Maintenance dose of 1 to 2 g/kg following exchange transfusion in the first 7 days and then up to 1 g/kg weekly, as required. Maternal: Maintenance dose of 1 g/kg adjusted body weight (to a maximum dose of 100 g) weekly from 18 weeks’ gestation until delivery.