Hemolytic disease of the fetus (HDF), prevention (i.e., maternal)
Recommended Indications in which IG can be used
Order Number: H4-HDF
| Recommendations | IVIG may be considered in severe disease when there are maternal antibodies against fetal antigens and a high risk of early fetal hydrops or death. Management should be under the direction of a high-risk obstetrician or maternal-fetal medicine specialist, with assistance from hematology as appropriate. |
| Dose/Frequency of Administration | 1 g/kg adjusted body weight (up to a maximum dose of 100g) weekly throughout pregnancy. |