Pyoderma gangrenosum
Recommended Indications in which IG can be used
Order Number: D2-PG
| Recommendations | IG may be considered in patients with significant pyoderma gangrenosum, as diagnosed by a dermatologist, when other therapies are ineffective or contraindicated. The diagnostic criteria for pyoderma gangrenosum should be met, and the relevant differential diagnoses (i.e., infections) must be excluded. |
| Dose/Frequency of Administration | Induction: 2 g/kg adjusted body weight divided over 2 to 5 days. Maintenance: 1 to 2 g/kg adjusted body weight divided over 2 days, every 4 weeks for 4 to 6 cycles. If there is no clinical response after 3 to 6 treatment cycles, IVIG should be discontinued. |