{"id":12649,"date":"2025-01-27T14:46:30","date_gmt":"2025-01-27T19:46:30","guid":{"rendered":"https:\/\/transfusionontario.org\/?p=12649"},"modified":"2025-01-27T15:40:05","modified_gmt":"2025-01-27T20:40:05","slug":"lamberteaton-myasthenic-syndrome-igum","status":"publish","type":"post","link":"https:\/\/transfusionontario.org\/en\/lamberteaton-myasthenic-syndrome-igum\/","title":{"rendered":"Lambert\u2013Eaton Myasthenic Syndrome (LEMS)"},"content":{"rendered":"\n<h2 class=\"wp-block-heading has-text-color has-link-color has-medium-font-size wp-elements-036f609a813ebf7c494f7208c56cbbdc\" style=\"color:#477d6c\"><strong>Recommended Indications in which IG can be used<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading has-black-color has-text-color has-background has-link-color has-small-font-size wp-elements-8b968f7d9d4566f60e59df7686bbe88c\" style=\"background-color:#a5cbbf\"><strong>Order Number: N5-LEMS<\/strong><span style=\"font-size: medium; font-weight: 400; white-space-collapse: collapse;\"><\/span><\/h3>\n\n\n\n<figure class=\"wp-block-table is-style-regular\"><table><tbody><tr><td><strong>Recommendations<\/strong><\/td><td>IVIG is recommended as an option for treatment. Maintenance therapy with IVIG may be used in patients who show objective evidence of clinical improvement with IVIG therapy but have incomplete response to oral maintenance therapies.<span style=\"font-size: medium; white-space-collapse: collapse;\"><\/span><\/td><\/tr><tr><td><strong>Dose\/Frequency of Administration<\/strong><\/td><td><strong>Induction: <\/strong>2 g\/kg adjusted body weight divided over 2 to 5 days.<br><br><strong>Maintenance:<\/strong> 0.4 to 1 g\/kg adjusted body weight, every 2 to 6 weeks. A maximum dose of 2 g\/kg may be given in any 4-week period.<br><br>Once the patient\u2019s condition has stabilized, consider titrating the dose and\/or the treatment interval to the lowest dose necessary to maintain clinical effectiveness. It is preferable to discontinue IVIG in favour of oral immunosuppressants, where possible.<span style=\"font-size: medium; white-space-collapse: collapse;\"><\/span><\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Recommended Indications in which IG can be used<\/p>\n<p>Order Number: N5-LEMS<\/p>\n","protected":false},"author":16,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":true,"_price":"","_stock":"","_tribe_ticket_header":"","_tribe_default_ticket_provider":"","_ticket_start_date":"","_ticket_end_date":"","_tribe_ticket_show_description":"","_tribe_ticket_show_not_going":false,"_tribe_ticket_use_global_stock":"","_tribe_ticket_global_stock_level":"","_global_stock_mode":"","_global_stock_cap":"","_tribe_rsvp_for_event":"","_tribe_ticket_going_count":"","_tribe_ticket_not_going_count":"","_tribe_tickets_list":"[]","_tribe_ticket_has_attendee_info_fields":false,"_EventAllDay":false,"_EventTimezone":"","_EventStartDate":"","_EventEndDate":"","_EventStartDateUTC":"","_EventEndDateUTC":"","_EventShowMap":false,"_EventShowMapLink":false,"_EventURL":"","_EventCost":"","_EventCostDescription":"","_EventCurrencySymbol":"","_EventCurrencyCode":"","_EventCurrencyPosition":"","_EventDateTimeSeparator":"","_EventTimeRangeSeparator":"","_EventOrganizerID":[],"_EventVenueID":[],"_OrganizerEmail":"","_OrganizerPhone":"","_OrganizerWebsite":"","_VenueAddress":"","_VenueCity":"","_VenueCountry":"","_VenueProvince":"","_VenueState":"","_VenueZip":"","_VenuePhone":"","_VenueURL":"","_VenueStateProvince":"","_VenueLat":"","_VenueLng":"","_VenueShowMap":false,"_VenueShowMapLink":false,"footnotes":""},"categories":[398],"tags":[],"class_list":["post-12649","post","type-post","status-publish","format-standard","hentry","category-neurology-indications"],"acf":[],"_links":{"self":[{"href":"https:\/\/transfusionontario.org\/en\/wp-json\/wp\/v2\/posts\/12649","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/transfusionontario.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/transfusionontario.org\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/transfusionontario.org\/en\/wp-json\/wp\/v2\/users\/16"}],"replies":[{"embeddable":true,"href":"https:\/\/transfusionontario.org\/en\/wp-json\/wp\/v2\/comments?post=12649"}],"version-history":[{"count":0,"href":"https:\/\/transfusionontario.org\/en\/wp-json\/wp\/v2\/posts\/12649\/revisions"}],"wp:attachment":[{"href":"https:\/\/transfusionontario.org\/en\/wp-json\/wp\/v2\/media?parent=12649"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/transfusionontario.org\/en\/wp-json\/wp\/v2\/categories?post=12649"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/transfusionontario.org\/en\/wp-json\/wp\/v2\/tags?post=12649"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}